- What prosthetic group is present in E1 of the PDH complex?
- Is the reaction turning pyruvate into acetyl-CoA and CO2 (via PDH complex) reversible or irreversible?
- Is NAD+ the oxidized or reduced state?
- NAD+/NADH can carry how many electrons?
- The word "oxidative" in "oxidative decarboxylation" indicates:
- Is NADH in the oxidized or reduced state?
- Pyruvate undergoes ___________________ to produce acetyl CoA.
- NAD+/NADH can be derived from which vitamin?
- In contrast to the mitochondrial beta oxidation, the first enzyme in peroxismal Beta oxidation introduces
- after a mixed meal containing carbohydrate, the major fuels used by the liver are?
- The figure on the right, Km is indicated at
- The side chains of amino acids that make up the catalytic triad of chymotrypsin contains?
- When a nucleophile present in the enzyme attacks an electrophilic substrate to form an enzyme-substrate intermediate, this is an example of ____________ catalysis.
- Human myoglobin and hemoglobin can bind oxygen by a protein-bound heme. The prosthetic group, heme, encompasses a _______________ ion.
- The catalytic triad of chymotrypsin is composed of His57 and ________________
- Priming of the S protein of SARS-CoV-2, proteolytic cleavage of S1/S2 and S2', is crucial for virus entry. SARS-CoV-2 has a PRRA insert indicating _
- Ka describes the equilibrium between the complex and the unbound components, what is Kd (formula at the right)?Ka = [PL]/[P][L] = 1/Kd
- Multisubunit proteins, conformational changes in one subunit can affect the others and is called?
- Conformational changes may occur upon ligand binding (for instance hexokinase). How is this mechanism called? ___________
- Which one of the following are common catalytic reaction mechanisms in enzyme active sites? ______ catalysis.