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Peptides that bind to a particular MHC isoform usually have either the same or chemically similar amino acids at two to three key positions that hold the peptide tightly in the peptide-binding groove of the MHC molecule. These amino acids are called _____ and the combination of these key residues is known as its _____.alleles; allotypesanchor residues; peptide-binding motifallotype; haplotypesinvariant chains; haplotypesrestriction residues; MHC allotype.

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