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The immunological consequence of severe combined immunodeficiency disease (SCID) caused by a genetic defect in either RAG-1 or RAG-2 genes islack of somatic recombination in T-cell receptor and immunoglobulin gene locilack of somatic recombination in T-cell receptor locilack of somatic recombination in immunoglobulin locilack of somatic hypermutation in T-cell receptor and immunoglobulin locilack of somatic hypermutation in T-cell receptor loci.

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