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What is required for B cells to switch isotype and increase antibody affinity?
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- T cells recognize antigen when the antigenforms a complex with membrane-bound MHC molecules on another host-derived cellis internalized by T cells via phagocytosis and subsequently binds to T-cell receptors in the endoplasmic reticulumis presented on the surface of a B cell on membrane-bound immunoglobulinsforms a complex with membrane-bound MHC molecules on the T cellbears epitopes derived from proteins, carbohydrates, and lipids.