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Il y a donc constamment polymérisation - dépolymérisation aux extrémités du microtubule ce qui, en fonction des circonstances, peut conduire à la disparition du microtubule si la dépolymérisation est plus rapide ou à la croissance du microtubule si la polymérisation est plus efficace. C'est ce que l'on appelle l'instabilité dynamique.
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