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Le muscle oblique supérieur de l'œil s'insère juste à côté de l'anneau tendineux commun sur l'os sphénoïde. Il se dirige en avant le long du bord médial de l'orbite jusqu'à ce que qu'il atteigne une poulie fibro cartilagineuse, qui est insérée dans la fossette trochléaire de l'os frontal. Il se termine en s'insérant sur le cadran postérieur externe du globe oculaire.
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