- Phospholipids have aa. Polar Head & Polar Tailb. Nonpolar Head & Nonpolar Tailc. Nonpolar Head & Polar Taild. Polar Head & Nonpolar Tail
- Most drugs are absorbed from which part of the GI tract?a. Buccal cavityb. Stomachc. Small intestined. Large intestine
- Villi have what effect on the surface area of the small intestine?a. Increases surface area 10 foldb. Increases surface area 20 foldc. Increases surface area 100 foldd. Decreases surface area
- According to Fick's law, the rate of diffusion ___________ as a membrane's surface area increasesa. Increasesb. Decreasesc. Stays the same
- The nurse should remove the _______ in a hearing aid when it is not being worn
- Salicylic acid, the carboxylic acid has a pKa of 3. It will be more ionized at...a. pH above 3b. pH equal to 3c. pH below 3
- Weak bases will remain ionized in the __________, and therefore are not absorbeda. Liverb. Stomachc. Small Intestined. Large intestine
- Ephedrine, a basic secondary amine, has a pKa of 9.5. It will be more ionized at....a. pH above 9.5b. pH equal to 9.5c. pH below 9.5
- Alprazolam has a log p of 2.5. What is K?a. 0.398b. 9536c. 316d. 398
- For bases, if the pH > pKa, the drug will bea. Ionizedb. Unionized
- The measure of the extent of absorbtiona. Cmaxb. Tmaxc. AUC
- For acids, if the pH < pKa, the drug will be a. Ionizedb. Unionized
- Microvilli have what effect on the surface area of the small intestine?a. Increases surface area 10 foldb. Increases surface area 20 foldc. Increases surface area 100 foldd. Decreases surface area
- For acids, if the pH > pKa, the drug will bea. Ionizedb. Unionized
- Facilitated absorption of drugs from the intestine requires energy derived from hydrolysis of ATPa. Trueb. False
- Passage through fluid-filled spaces between cellsa. Paracellularb. Transcellular
- A route of drug administration that avoids the first-pass effect is sublinguala. Trueb. False
- A drug given intravenously results in an AUC of 400mg.h/L. If the same dose of the drug is given orally results in an AUC of 300mg.h/L what percentage of the oral dose reaches systemic circulation?a. 0.5%b. 33%c. 50%d. 75%
- Which of the following statements best describes the factor F in relation to absorption of drugsa. Rate of absorption of the administered drug into systemic circulationb. Amount of administered drug that reaches systemic circulationc. Fraction of the administered dose that reaches systemic circulationd. Amount of drug reaching target site
- The approximate indicator of absorption rate. The shorter this is, the faster the absorptiona. Cmaxb. Tmaxc. AUC