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1. Osteclaster binder till osteopentin (RGD- innehållande protein i matrix) genom integriner.2. Protoner produceras av karboanhydras enzymet i cellen.3. En protonpump i plasmamembranet försurar den isolerade resorptionsavdelningen.4. Kloridjoner kmpenserar för den positiva laddningen (HCL bldas).5. benets mineral upplöses i den sura miljön.6. Lysosomala enzymer utsöndras för att bryta ner det organiska matrix.
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