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5. The threshold potential is controlled by calcium.a. Hypocalcemia lowers the threshold toward the resting potential, thereby increasing the likelihood that unwanted (spontaneous) action potentials will develop in nerve and muscle.b. The symptoms of hypocalcemia are related to an increased firing of motor neurons (possibly leading to tetany) and an increased firing of sensory neurons (tingling of fingers and lips).c. With hypercalcemia, threshold moves away from the resting potential, which decreases excitability.This explains why calcium protects the heart of the patient who is hyperkalemic.
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