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8. Anne and Geoff are in your afternoon clinic discussing their desire to start a family. They are concerned because one of Anne's friends has a child with CF and they would like to know if they have any risk factors. Anne's maternal aunt has a son with CF. Anne's parents are from Russia, and Geoff's are from England. Both Anne and Geoff are heavy smokers. Which of the following is/are the greatest CF risk factors/ for their future offspring?a. Family HX of CF is a risk factor as both Anne' and Geoff's ethnicityb. Family HX of CF is a risk factor; ethnicity is not a risk factorc. CF is multifactorial and neither ethnicity nor the family member with CF is a specific risk factord. CF is a spontaneous mutation; there are no specific risk factorse. CF is an epigenetic phenomena that is affected by in utero exposure to tobacco smoke
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