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A 14 year old spayed female poodle presented with progressive hair loss. Physical examination revels sparse truncal hair, thin skin, hyperpigmented areas and 3 areas of thickened skin that feels slightly gritty. OWner reports that skin problem does not bother the dog. Blood sample is taken and 2hr later, owner phones and reports that the dog has a huge bruise at site of venepuncture. The most likely diagnosis is?

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