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A 44-year-old woman is seen in the hypertension clinic after being referred by her GP with persistently elevated blood pressures above 180/120 mmHg that are resistant to simple and combination anti-hypertensives. She has also been experiencing palpitations, tremors, and sweating despite not exercising over the last month.Further investigation is undertaken. An abdominal CT shows a 1cm mass on her left adrenal gland suggestive of phaeochromocytoma and she has highly elevated serum and urine catecholamine levels.By what mechanism is this hormone achieving the pathological effects seen in this patient?A - G-protein coupled receptorsB - guanylate cyclase-coupled receptorsC - ligand-gated ion channelD - receptor tyrosine kinaseE - sodium channel
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