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A 68-year-old female patient tells her physician of being "cold all the time" and recent weight gain, with no change in diet. The doctor orders a TSH level, and the laboratory reports a value of 8.7 µU/ mL (8.7 IU/L) (reference range = 0.5 - 5.0 µU/mL [0.5 - 5.0 IU/L]). This patient most likely has:
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