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AML clinical features:- Most patients present within weeks - few months --> _____, _____, and _____ (fatigue, fever, spontaneous mucosal and cutaneous bleeding similar to ALL)- Procoagulants and fibrinolytic factors released by leukemic cells --> Exacerbate _____ tendency (infections are frequent)- CNS spread is _____ common than in ALL- AML remains a _____ disease --> Overall survival in all patients is only 15-30% with conventional chemotherapy
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