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B. nondisjunction during mitosisIf nondisjunction occurs during a mitosis event post fertilisation it will result in a mixture of cells with different chromosome numbers. For example, if non disjunction of chromosome 8 occurs early in female development, two cell lines develop: 45, XX, -8 and 47, XX +8. These will be in addition to the 46, XX. The 45, XX - 8 cell line does not survive. Thus the karyotype of the individual becomes 46, XX/47,XX,+8

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