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Dégénérescence axonale rétrograde jusqu'au nœud de Ranvier susjacent.Atrophie du corps cellulaire max à1 semaine puis nécrose complète ourégénération.La nécrose complète est plus fréquente si la lésion est proche ducorps cellulaireLa régénération est maximale à partir de J18, jusqu'à 6 mois
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