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En translokation här en hel arm transponeras mellan två kromosomer.Klinisk relevant endast mellan akrocentriska kromosomer där p-axeln är så kort att den knappt behövs (13, 14, 15, 21 & 22).En balanserad Robertsonsk translokation orsakar inte en abnormal fenotyp medan en obalanserad orsakar sjukdom (exv. ärftlig trisomi 21).
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