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Förklaringar till att friska par kan få barn med en autosomalt dominant sjukdom:• Sjukdomen är genetiskt heterogen och ärftligheten är en annan. Kan därför resultera i att paret får flera sjuka barn.• Sjukdomen orsakas av en nymutation• Klon av könsceller med en mutation (germinal mosaicism) hos någon av föräldrarna.Detta kan resultera i att paret får flera sjuka barn.• Nedsatt penetrans, vilket också kan resultera i att paret får flera sjuka barn.• Varierande expressivitet, vilket också kan resultera i att paret får flera sjuka barn.• Annan biologisk far.
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