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For each of the cellular conditions listed below from (a) to (j), indicate if phosphofructokinase-1 activity is stimulated or inhibited compared to that in control cells.Increased fructose-2,6-bisphosphate levels.The conformational equilibrium is shifted toward the T state (inactive).AMP is bound to the allosteric effector site and ATP is bound to the catalytic site (stimulated).Decreased fructose-2,6-bisphosphate levels.ATP is bound to both the catalytic site and the allosteric effector site. Increased levels of both ADP and AMP.Increased citrate levels in the cell.The conformational equilibrium is shifted toward the R state (active).
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