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- children have increased risk for lead exposure, as well as for adverse health effects. the reasons include all of these except-hand to mouth exposure-children eat and drink more per unit of body weight than adults-lead absorption in the GI tract is substantially higher in children (about 50% compared with about 10% in adults)-there is a greater prevalence of nutritional deficiencies (iron, vitamin D) among children, which enhance absorption of lead from the GI tract-the blood brain barrier is not yet fully developed in young children-all of the above are true and are factors that contribute to children's increased sensitivity to Pb exposure