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In the middle ins the metabolic pathway on the left is the disorders when the enzyme is missing and on the right is the enzyme that catalyzes a specific step in this pathway. Phenylalanine is a carbon atom connected to H, NH2, COOH, CH2 hexagon rings. When acted by phenylamine hydroxylase it becomes tyrosine and mutation causes phenylketonuria. Tyrosine is a carbon atom attached to H, COOH, NH2, CH2 hexagon ring HO. This when acted by tyrosine aminotransferase gives p-hydroxyphenolypyruvic acid. This when acted by hydroxyphenylpyruvate oxidase gives homogentisic acid and its mutation can cause tyrosinosis. When homogentisic acid oxidase acts upon gives maleylacetoacetic acid and its mutation give alkaptonuria.If a person inherits two mutant genes that encode hydroxyphenylpyruvate oxidase, what metabolite will accumulate?

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