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Les toxines bactériennes augmentent la production d'AMPc dans les entérocytes ce qui provoque la production de prostaglandines => Augmentation de la contraction lisse et de la motilité.Physiologiquement, les enképhalines empêchent la sortie d'eau en empêchant la formation d'AMPc (ce qui engendre une libération d'eau importante).
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