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Name: Glucocorticoids: prednisone, prednisolone, dexamethasone, cortisone, hydrocortisone MOA: bind to glucocorticoid receptor to alter DNA synthesis Indications: Suppress inflammation, allergy and immune response. Treatment of adrenal insufficiency. Adverse Effects: Development of cushingoid syndrome (cushing features: buffalo hump, moon face, HTN, central obesity), weight gain, cataracts (cat eye), increased IOP (hat), fluid retention/HTN, increased risk of AFIB, dyslipidemia, adverse GI effects, osteoporosis, myopathy, mood disorders, psychosis, memory impairment, hyperglycemia, increased risk of infection Contraindications: hypersensitivity, systemic fungal infection, undiagnosed malignancy, herpetic keratitis, administration of live vaccines, use with caution in HF, HTN, diabetes, GI disease, hepatic impairment, myasthenia gravis Interactions:Notes:

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