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Patients presenting in DKA are normally significantly fluid deplete and should be started on a fluid regime of 1L 0.9% sodium chloride over an hour, followed but 2x 1L 0.9% sodium chloride over 2 hours etc. An IV infusion of insulin should also be started at a rate of 0.1 units/kg/hour. If blood glucose falls below 15mmol/L but the patient is still acidotic with ketones then an infusion of=== should be started, along with the 0.9% sodium chloride, and insulin continued.

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