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Retinoic acid embryopathy: - _____ _____ and its analogs have considerable teratogenic potential - 1/3 of pregnancies exposed in 1st trimester to the synthetic retinoid isotretinoin, commonly prescribed to treat acne - Features: _____ malformation, ear anomalies, _____ _____ disease (great vessel anomalies), tracheoesophageal fistula - Vitamin A intake is limited to _____ IU/day of retinoic acid
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