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Start DNA synthesis:- Helicase: separated DNA strands- Primase: produce a primer (small fragment of RNA)DNA synthesis:- DNA polymerase extend an existing 3’end (needs a primer)synthesis 5’=> 3’ directionproof-reading activityRemove primers:- Exonuclease: remove primers- DNA pol: fills the gaps with DNA nucleotides- Ligase: formation of the phosphodiester bond
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