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This patient has Cushing's syndrome. Due to increased glucocorticoid production, symptoms include weight gain, thinning skin, and abdominal striae such as those seen in this patient. Hypertension is another common finding also seen here. Laboratory tests may reveal === The best test to diagnose Cushing's syndrome is the low-dose dexamethasone test. It is the most sensitive test and involves giving a low dose of dexamethasone and monitoring the morning cortisol levels as those with Cushing's syndrome will not show suppressed cortisol levels despite dexamethasone.
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