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Which ONE of the following statements about osteoarthritis (osteoarthrosis; OA) is true?☐ A. Ageing and OA have similar effects on the extracellular matrix of cartilage ☐ B. An increase in joint space is a characteristic feature of OA☐ C. Cartilage over-hydration is an early event in osteoarthritis☐ D. OA is considered as a single disease☐ E. The stimulation of the auto-immune response is a primary event in OA

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