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XX : remplace un codon qui code pour un acide aminé par un codon stop 🡪 pathogènes. Entraîne la traduction d'une protéine courte 🡪 au moment de la traduction la protéine anormale (trop courte) est rapidement dégradée. Entraîne une absence de protéine. Généralement pathogènes
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