- This is because you want the O2 to come off so the tissues can use it - if it stays saturated, you may deprive the tissues of O2
- Right (allows O2 to be released easier)- If tissues are making CO2, they used their O2 for those that need it (Bohr Effect)
- A precursor antigen- necessary in order to make any of the other antigens - autosomal dominant
- When we shift our curve, since the strength of binding is weaker, hemoglobin is more likely to release oxygen
- It increases the amount of CO2, causing a right shift- This helps tissues get O2 from hemoglobin
- Shift to the Left (higher binding affinity)- caused by the gamma chains
- Which of the following is an abnormal lateral curvature of the vertebral column often seen in the thoracic region?
- It is inversely proportional to binding affinity (measurement of strength)
- there would be a higher p50, but lower binding affinity- however, more O2 concentration is needed to achieve this
- Amount of O2 bound to Hg is dependent on how much O2 in the plasma
- The pelvic girdle does not include the ________.
- Hemoglobin is completely full of O2- 4 binding on every hemoglobin
- Start at 50% of Hb-O2 sat on graph and track its intersection point on the X-axis (perpendicular)
- It is easier to release O2 from hemoglobin- however more O2 concentration needed for this same effect
- partial pressure of O2 (concentration) required to have 50% hemoglobin saturation
- Hb-O2 Saturation (%)- how much O2 we are carrying/how much is bound to hemoglobin- 0 to 100%
- Which of the following is not a movement that can occur between vertebrae?
- Lower p50, which means an increase in binding affinity - HgB holding on more tightly
- We don't really encounter it as much unless we have been exposed by something with this antigen on it - should be producing Anti-D antibodies but don't until exposure
- Partial Pressure of O2 (pO2)- concentration of O2 in the plasma