- larger solids can be retained in the stomach for how long?
- which has a larger blood flow?a. stomachb. intestine
- all drugs are better absorbed:a. stomachb. intestine
- what is the ideal method for monitoring drug concentrations?
- what is the rate limiting step of PK of a drug?
- dissolution is:a. unidirectionalb. bidirectional
- biotransformation determines what in the conversion from active to inactive metabolite?
- Acetic acid, sulfate, glutathione, methyl: microsomal or non?Phase I or II?
- biotransformation converts the drug into what to make it more easily eliminated
- T/F phase II reactions can act on the metabolic product or the original drug.
- rate of elimination is directly proportional to what?
- biotransformation determines what in the conversion from prodrug to active drug?
- which order process are most drugs eliminated?
- What are primarily responsible for the first pass effect?
- Glucuronide conjugation: microsomal or non?Phase I or II?
- What determines clinical duration of a single dose of CNS drug?
- T/F most drug excretion is through the kidneys
- if the pKa of the drug is equal to the pH, then what percent of the drug is charged?
- Bioavailability of PO, IM, and any route other than IV
- drugs that distribute into total body water have a Vd of?