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Pathophysiology
Explore questions in the Pathophysiology category that you can ask Spark.E!
- Which cellular structure is responsible for processing and packing secretory proteins and receives properly folded proteins from the rough ER and packages them into vesicles for secretion?
- Which term refers to injury to cells and to extracellular matrix that ultimately leads to tissue and organ injury, which determines the morphologic and clinical patterns of diseases?
- Plasma membrane functions:- _____ and _____ acquisition- Provides a _____ to passive diffusion of large or charged molecules (membrane transport)- _____ mechanisms, scaffolding, and _____
- Which term refers to the study of the disordered physiological processes associated with disease or injury?
- Which term refers to the causes of disease?
- Alcoholic steatohepatitis pathophysiology:- _____ cells secrete cytokines- _____ cells get activated
- TIA or Ischemic stroke?- Infarction of brain, spinal cord, or retinal cell death due to ischemia, based on neuropathologic, neuroimaging, and/or clinical evidence of permanent injury
- Which term refers to a heterogeneous group of disorders caused by mechanisms other than metastases, metabolic and nutritional deficits, infections, coagulopathy, or side effects of cancer treatment?
- PD clinical features:- _____: “rest tremor” and intermittent- _____: generalized slowness of movement- _____: increased resistance to passive movement about a joint- _____ _____: an impairment of postural reflexes that cause a feeling of imbalance and a tendency to fall
- Which type of liquid biopsy?- General term that applied to both tumor and normal DNA fragments not associated with cells
- Grading or Staging?- Based on degree of differentiation
- Alcoholic steatosis pathophysiology:- Accelerated hepatic _____- Defective hepatic _____ export- Impaired _____ liver secretion
- HH is caused by a mutation in which gene that causes decreased activity of which molecule?
- IDH-mutant glioma pathophysiology:- Elevated _____ levels- Cause _____ cell suppression by: _____ “_____” effect, _____ ”_____ _____ effect”
- Which term refers to a tumor's tendency to metastasize to specific organs that indicates the cancer cells' ability to adopt to and colonize secondary tissues?
- Which type of liquid biopsy?- Extracellular DNA from cancer cells that have undergone cell death
- True/False: There are only tumor-promoting microbiomes involving particular bacterial species that can affect the incidence and pathogenesis of colon tumors.
- TIA or Ischemic stroke?- Episode of neurologic abnormalities caused by focal brain, spinal cord, or retinal ischemia, without acute infarction
- Hepatic encephalopathy in ALF pathophysiology:- Increase in _____ concentrations passing the _____ results in increase in _____ in the brain- _____ swelling --> Cerebral _____ --> Intracranial _____ --> Neuronal dysfunction
- Which jaundice classification?- Type: unconjugated and conjugated- Cause: defective conjugation; abnormal excretion of bilirubin