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Leukemia etiology:- Chromosomal _____: and other acquired mutations (major role in leukemias)- Inherited _____ factors: genetic disease that promote genomic instability (Bloom syndrome, Down syndrome, neurofibromatosis type I)- _____: HTLV-1, EBV, HHV-8- Chronic _____ stimulation: H. pylori infection with gastric B cell lymphoma- _____ factors: radiotherapy, certain chemotherapy- _____
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